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Note: Click on the session titles (in green) to view a full list of presentations in each concurrent track.
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THURSDAY, APRIL 7, 2022
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1:00 PM – 6:00 PM |
Registration Desk Open
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5:00 PM – 7:00 PM |
Welcome Reception
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7:00 PM – 8:30 PM |
IBE Leadership Council Meeting
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FRIDAY, APRIL 8, 2022
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7:00 AM – 6:00 PM |
Registration Desk Open
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7:00 AM – 8:00 AM |
Continental Breakfast
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8:00 AM – 9:15 AM |
Opening Remarks and Keynote Presentation
Opening Remarks: Sabrina Jedlicka, IBE President
Keynote Presentation:
Biological Engineering: The Merger of (Two) Source Streams Produces a Mighty River
Dr. Linda Griffith, School of Engineering Teaching Innovation Professor of Biological and Mechanical Engineering, Massachusetts Institute of Technology
More Information
The spring that gave rise to the original source stream of IBE in 1995 was the vision Prof. Brahm Verma had for a new discipline of engineering based in modern molecular life science. His background in agricultural engineering provided a powerful perspective of pan-organismal principles – from microbes to plants to animals – underlying the integration of biophysical and biochemical phenomena governing all aspects of living systems, from an engineering analysis-design-synthesis perspective. In parallel fashion, in the mid-1990s, many investigators applying engineering principles to various aspects of human health gravitated toward similar unifying principles for mammalian (mostly human) systems, applying “mine, model, measure, manipulate” engineering approaches to modern molecular life sciences. These investigators began to make clear semantic distinctions between “biomedical engineering” (application of many different disciplines of engineering to medicine), and “biological engineering” (application of engineering analysis, design, and synthesis to modern molecular life sciences) and thus gave rise to a second source stream for “Biological Engineering”. With the explosion of activity in the fields of the microbiome, nutrition, synthetic biology, and others, these two streams have effectively merged in harmonious fashion, united by a firm commitment to an engineering curriculum focused on essential science and engineering principles that are application agnostic. This talk will highlight the intertwined emergences of these streams, and their merger, with examples from research and education at MIT and UGA – including the surprising and unexpected ways “biological engineering” broadly writ is transforming the field of gynecological research.
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9:15 AM – 9:30 AM |
Break & Poster Set-Up
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9:30 AM – 12:00 PM |
Concurrent Sessions
- Synthetic Biology and Metabolic Engineering
Track Chairs: Yajun Yan and Xue Gao
- 9:30 AM: Dynamic Behavior Exploration of TrpR-based Biosensor System by Regulator and Operator Engineering
Xinyu Gong, Ruihua Zhang, Jian Wang and Yajun Yan
- 9:45 AM: Establishing microbial biosynthetic platforms for valuable plant natural products
Jixun Zhan
- 10:00 AM: Programming Gene Expression in Multicellular Organisms for Physiology Modulation through Engineered Bacteria
Qing Sun
- 10:15 AM: Altering phosphofructokinase (PfkA) in Escherichia coli for the production of NADPH-requiring biochemicals
Hemshikha Rajpurohit and Mark Eiteman
- 10:30 AM: Altering pyruvate dehydrogenase in Escherichia coli for the production of pyruvate and pyruvate-derived biochemicals
Chris Moxley and Mark Eiteman
- 10:45 AM: Biocatalytic Production and Purification of High-Value Methylxanthines
Meredith Mock, Ryan Summers, Shelby Mills, Ashley Cyrus, Hailey Campo, Tyler Dreischarf and Sydney Strock
- 11:00 AM: Identification of a novel glucuronyltransferase from Streptomyces chromofuscus ATCC 49982 for natural product
glucuronidation Jie Ren, Caleb Barton and Jixun Zhan
- 11:15 AM: Modifying citrate synthase activity to increase acetyl-CoA availability in Escherichia coli
Jeffrey Dodelin and Mark Eiteman
- 11:30 AM: Multiplex base-editing enables combinatorial epigenetic regulations for genome mining of fungal natural products
Xue Gao, Fanglong Zhao and Zhiwen Liu
- 11:45 AM: GPCR-based sensors for biomedical applications
Pamela Peralta-Yahya
- Biological Sensing and Diagnostics
Track Chair: Jonathan Claussen
- 9:30 AM: An Electrochemical Biosensor for Rapid Detection of Listeria Monocytogenes for Food Safety Applications
Or Zolti, Baviththira Suganthan and Ramaraja Ramasamy
- 9:45 AM: An Impedimetric Biosensor Platform to Detect Campylobacter jejuni
Baviththira Suganthan, Ashley Rogers, Clay Crippen, Hamid Asadi, Christine Szymanski and Ramaraja Ramasamy
- 10:00 AM: Development of a field-deployable sensor for the detection of glyphosate in water samples
David Bahamon, Geisianny Moreira and Diana Vanegas
- 10:15 AM: Development of Low-cost Sensors for the Detection of Mercury in Artisanal Gold Mining Communities of Southwest Colombia
Kelli McCourt, Paulina Rojas-Lamos, Lisseth Casso-Hartmann, Irene Velez-Torres and Diana Vanegas
- 10:30 AM: DIY Photon Flux Quantum Sensor for a Tight Budget
Mark Haidekker, Marc van Iersel and Reeve Legerndre
- 10:45 AM: DNA-based biosensor for the detection of StxA gene in E. coli O157:H7
Emma Dester and Evangelyn Alocilja
- 11:00 AM: Extraction and Detection of Staphylococcus aureus from Food Matrices
Chelsie Boodoo, Emma Dester and Evangelyn Alocilja
- 11:15 AM: Laser-induced graphene open microfluidics and electrochemical biosensors for in-field multiplexed fertilizer and pesticide monitoring
Zachary Johnson, Robert Hjort, Nathan Jared, Carmen Gomes and Jonathan Claussen
- 11:30 AM: Quality Control for LIG electrodes: Toward scalable and rapid saliva diagnostics
Yifan Tang, Diana Vanegas and Eric McLamore
- 11:45 AM: Rapid and label-free foodborne pathogen Listeria monocytogenes detection based on nanoplatinum and stimuli-responsive brushes
Daniela Oliveira, Suleiman Althawab, Eric McLamore and Carmen Gomes
- 12:00 PM: Survey of Sensing Methods for Early Seizure
Alerts Ashley Galanti and Mark Haidekker
- Circular Food & Agriculture Systems
Track Chair: Kurt A. Rosentrater
- 9:30 AM: Industrial Ecology of Circular Bioeconomy
Brahm P. Verma
- 9:45 AM: Envisioning a circular fruit and vegetable production systems: A case study with life cycle assessment of blueberry production in Georgia
Sudhagar Mani, J Mullen and Paige Weiler
- 10:00 AM: Hydroponic Wastewater Characterization and Nutrient-Use Assessment to Evaluate Biological Treatment Suitability for Recirculating Irrigation Solution
Kelsey Vought, Ana Martin-Ryals and Haimanote Bayabil
- 10:15 AM Hydroponic Wastewater Reuse for Sustainable Urban Agriculture
Amanda Tan, Diana Vanegas, Jeffrey Adelberg and Terry Walker
- 10:45 AM: Investigating co-culture of methanotrophs and cyanobacteria for polyhydroxybutyrate (PHB) production from anaerobic digester byproducts
Michelle Ezequelle, Florencia Corbo-Ferreira and Ana Martin-Ryals
- 11:00 AM: Resource Utilization in Heterotrophic Vs Autotrophic Marine Shrimp Production
David Brune
- 11:15 AM: The Mitigation of Gaseous Emissions from Poultry Litter: A Review of Biochar Application for Environmental Management
Sam O'Brien, Jacek Koziel, Baitong Chen and Andrzej Białowiec
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12:00 PM – 1:30 PM |
Lunch On Your Own
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1:30 PM – 2:45 PM |
Keynote Presentation:
Transforming Grain Production Systems for a Circular Bioeconomy Dr. Bruno Basso, MSU Foundation Professor Department of of Earth and Environmental Sciences, Department of Plant, Soil, and Microbial Sciences, Michigan State University
More Information
Grain production systems in the United States need to be transformed into more circular and sustainable systems to address the simultaneous challenges of resource depletion, environmental degradation, and increasing demand for food under the threat of climate change. Grain production in the U.S. is geographically dispersed and distant from large centers of national and global consumption (e.g., animal feeding operations, food processors, cities) with limited recycling of nutrients and energy, and a major source of non-point source pollution of air and water. In this talk I show that transformation of U.S. grain production systems into circular systems can be achieved using currently feasible digital, mechanical, and genetic technologies that close loops of nutrient and energy flows within the farm, through the optimization of land use choices and crop management. But widespread adoption of these circular systems by the large-scale commercial farms that produce most of the grain crops in the U.S. will depend critically on their profitability relative to the current linear system.
Bruno Basso is an agro-ecosystem scientist and University Foundation Professor in Department of Earth and Environmental Sciences at Michigan State University. His research deals with the long-term sustainability, circularity and resilience of agricultural systems, with particular focus on modeling water, and nutrients fluxes across agricultural landscapes under current and future climates. He holds global patents on AI, crop model systems to evaluate land productivity and environmental sustainability. He is the cofounder and chief scientist of CiBO Technologies.
He is a Fellow of the American Association for the Advancement of Science (AAAS); Soil Science Society of America (SSSA); American Society of Agronomy (ASA). He is the recipient of the 2021 Morgan Stanley Sustainability Solution Prize Collaborative; 2019 Outstanding Faculty Award at Michigan State University; 2016 recipient of the Innovation of the year award.
He serves on the Board of Agriculture and Natural Resources of the US National Academies of Sciences, Engineering and Medicine. He is a member of the Biological and Environmental Research Advisory Council (BERAC), Department of Energy, Office of Science; and he is the scientific advisor of several private and nonprofit organizations.
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2:45 PM – 3:00 PM |
Break
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3:00 PM – 5:00 PM |
Concurrent Sessions
- Biomaterials and Nanomaterials
Track Chair: Sabrina Jedlicka
- 3:00 PM: Applications of Cerium Oxide Nanoparticle Infused Chitosan-PVA Hydrogel for Wound Healing
Lucas Tavares, Bryan Shim, Ruchi Borole and Vladimir Reukov
- 3:15 PM: Cerium Oxide Nanoparticles: A Promising Outlook into Ophthalmic Applications
Mir Patel, John Burn and Vladimir Reukov
- 3:30 PM: Increasing Fibroblast Cell Metabolic Activity With the Addition of Nanoceria
Helly Patel, Anya Shroff and Hayley Cotton
- 3:45 PM: Optically activated immune modulatory proteins to dictate immune cell phenotypes and responses
Lacey Birnbaum, Priscilla Do, Biaggio Uricoli and Erik Dreaden
- 4:00 PM: Real time and Rapid Food Quality Monitoring by Sensory Film and Machine Learning
Zhaohui Tong and Karyn Pounds
- Biological Engineering Education
Track Chairs: Craig Forest and Maxine Jonas
- 3:00 PM: Nucleate; empowering the next generation of biotech leaders
Oliver Dodd
- 3:15 PM: Project-centric cross-disciplinary learning through the NEET (new engineering education transformation) program at MIT
Mehdi Salek, Linda Griffith and Maxine Jonas
- 3:30 PM: University pathway for commercializing undergraduate bioengineering student inventions
Craig Forest, Essy Behravesh, Lakshmi Dasi, Mercedes Gonzalez, Wilbur Lam, Joyelle Harris, Rahul Saxena, Raghupathy Sivakumar and Raymond Vito
- 3:45 PM: Enhancing Experiential Education with Biomakerspaces
Justin Buck
- 4:00 PM: Biological Engineering Experiments for STEM Experiential Learning at the K-14 Levels
James Dooley
- 4:15 PM: An educational board game for teaching bioenergetics and mitochondrial health
Leah Cuthill, Raj Rao and Shilpa Iyer
- 4:30 PM: Freeze-dried, cell-free technology and its applications to education
Ally Huang
- Public Health and Biological Engineering
Track Chair: Evangelyn Alocilja
- 3:15 PM: Electrochemical Methods of Detection for Rapid Diagnostics
Ramaraja Ramasamy
- 3:30 PM: Rapid and label-free detection of infectious pathogens based on graphene electrochemical immunosensors
Daniela Oliveira, Cicero Pola, Raquel Soares, Robert Hjort, Cassie Giacobassi, Shoumen Datta, Diana Vanegas, Eric McLamore, Jonathan Claussen and Carmen Gomes
- 3:45 PM: Graphene-based electrochemical immunosensors for rapid and label-free detection of SARS-CoV-2 in saliva
Cicero Pola, Sonal Rangnekar, Robert Sheets, Beata Szydlowska, Geisianny Moreira, Yifan Tang, Daniel Jenkins, Shoumen Datta, Eric McLamore, Mark Hersam, Diana Vanegas, Carmen Gomes and Jonathan Claussen
- 4:00 PM: Development of a low-cost enzyme-based biosensor for point-of-need saliva diagnostics of SARS-CoV-2
Geisianny Moreira, Lisseth Casso, Shoumen Datta, Eric McLamore and Diana Vanegas
- 4:15 PM: Connecting data science, decision science, and analytical electrochemistry: SARS-CoV-2 detection as proof of principle
Eric McLamore, Geisianny Moreira, Shoumen Datta and Diana Vanegas
- 4:30 PM: COVID Biosensor for Rapid Screening and Active Case Finding of SARS-CoV-2 Virus
Ruben Kenny Briceno, Alex Castaneda-Sabogal, Jimmy Alexi Rodriguez Juarez, Oscar Miranda Monzon, Zara Leon Gallardo and Evangelyn Alocilja
- 4:45 PM: Genomic-Phenotypic Approach to Rapid Antimicrobial Resistance Detection
Evangelyn Alocilja, Oznur Caliskan-Aydogan, Emma Dester, Chelsie Boodoo and Saad Sharief
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5:00 PM |
DAY ONE ENDS Dinner On Your Own
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SATURDAY, APRIL 9, 2022
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7:00 AM – 6:00 PM |
Registration Desk Open
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7:00 AM – 8:00 AM |
Continental Breakfast
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8:00 AM – 9:15 AM |
Keynote Presentation:
Engineering Microsystems and Computational Pipelines to Understand the Brain Dr. Hang Lu, Love Family Professor of Chemical & Biomolecular Engineering, Georgia Tech
More Information
My lab is interested in engineering micro systems and computational tools to address questions in systems neuroscience, developmental biology, and cell biology that are difficult to answer with conventional techniques. We are particularly interested in the questions of how the brain is assembled during development (and changes during aging) and information is processed by brain circuits. We work with a powerful genetic system - the free-living soil nematode C. elegans. I will introduce two sets of powerful mathematical and physics-based tools accessible by engineers to accelerate the biological understanding. By designing the microfluidic system cleverly taking advantage of miniaturization and automation, we can have exquisite control of the samples and experimental conditions, as well as accelerating the experimental throughput. In parallel, machine-learning approaches for computational analyses of data greatly reduce bias, enable automated and robust cell identification, tracking, and functional analyses, which will enable a variety of applications including gene-expression analysis, whole-brain imaging, and connectomics.
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9:15 AM – 9:30 AM |
Break & Poster Set-Up
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9:30 AM – 12:00 PM |
Concurrent Sessions
- Tools and Decision Support for Smart Agriculture
Track Chair: Eban Bean
- Sustainable, Bio-derived Fuels, Chemicals and Materials
Track Chairs: Maobing Tu
- 9:30 AM: Application of Machine Learning to predict the performance of biomass pyrolysis process
Ehsan Vasefi and Sudhagar Mani
- 9:45 AM: Effects of Vibrating screen sorting on chemical composition and calorific value of organic fraction of MSW
Maobing Tu and Yu Zhang
- 10:00 AM: Grinding and bulk flow performances of southern pine forest residue tissue fractions
Osayuwamen Osagie and Sudhagar Mani
- 10:15 AM: Looking Forward, Looking Back: Growth and Evolutions in Feed Coproduct Generation from the US Biofuels Industry
Kurt Rosentrater
- 10:30 AM: Optimization of different media components and fermentation parameters to maximize the production of hydrolytic enzymes using distillers dried grains with solubles (DDGS) by Aspergillus niger
Attia Iram, Ali Demirci and Deniz Cekmecelioglu
- 10:45 AM: Struvite precipitation for enhancement of nutrient removal in municipal wastewater using a rotating algae biofilm reactor
Parker Goldsberry and Ron Sims
- Biomedical Engineering and Tissue Engineering
Track Chairs: Edward A. Botchwey, Yu Huang, and Venkatakrishnan (Krish) Rengarajan
- 9:30 AM: Bioenergetic profiling of human induced pluripotent stem cells from mitochondrial disorders
Fibi Meshrkey, Kelly Scheulin, Raj Rao, Franklin West and Shilpa Iyer
- 9:45 AM: Light-Guided Immunotherapy via Cytokine-Polymer Conjugates
Lacey Perdue, Priscilla Do, Christopher Porter and Erik Dreaden
- 10:00 AM: Multivalent, T Cell-Engaging Cytokines for Leukemia Immunotherapy
Priscilla Do, Jodi Dougan, Rae Hunter, Christopher Porter and Erik Dreaden
- 10:15 AM: Manuka Honey Flavonoid Components Modulate Inflammatory Behavior in a Differentiated HL60 Model
Evan Main, Kian Ziai, James Huang and Gary Bowlin
- 10:30 AM: Anti-corrosive and biocompatible polymeric coating based on silk and cellulose nanocrystal on Mg-based orthopedic Implants
Hamid Asadi, Sama Ghalei, Hitesh Handa and Ramaraja Ramasamy
- 10:45 AM: Numerical Investigation of Aortic Hemodynamics and Vascular Stent-Grafts Using 4D Flow-MRI and Patient-Specific CFD Models
Scott Black, Craig Maclean, Pauline Hall Barrientos, Konstantinos Ritos and Asimina Kazakidi
- 11:00 AM: Engineer a Cancer-On-A-Chip Platform to Study Chemotactic Invasion of Glioblastoma Multiforme
Venkatakrishnan Rengarajan, Junnan Geng, Zachary Davis and Yu Huang
- Bioenvironmental Engineering
Track Chairs: Weilan Zhang and Yanna Liang
- 9:30 AM: Phytoremediation of per- and polyfluoroalkyl substances (PFAS) followed by hydrothermal liquefaction
Weilan Zhang and Yanna Liang
- 10:00 AM: Luxury Phosphorus Uptake in Algae Biofilms
Dylan Ellis and Ronald Sims
- 10:15 AM: Distribution of per- and polyfluoroalkyl substances (PFAS) in a soil-microbe-soybean system and their effects on functional genes involved in nitrogen fixation, nitrification and denitrification
Weilan Zhang, Tao Jiang and Yanna Liang
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12:00 PM – 1:15 PM |
Lunch On Your Own
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1:15 PM – 3:30 PM |
USDA/NIFA Convergence Workshop
Comprehensive Monitoring of Landscape Flux in Environmental Systems with an Emphasis on Rice Agriculture and Food Systems Dr. Benjamin Runkle
Recent Advances in Epidemiology, Surveillance, Control, and Elimination of Infectious Disease Dr. David Larsen
Environmental Microbiology, Biological Treatment, Pathogens and Risk Dr. Jennifer Weidhaas
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2:30 PM – 3:30 PM |
Bioethics Essay Contest Finalists
- Adapting Genomic Protections for the 21st Century
Kaden Wines, Filip To and Barton Moffatt
- Climate Change: Ethical Responsibilities of Developed Countries for Developing Countries
Jaden Storrer
- Do We Value Algorithms over Air Quality: Big Data’s Indirect Impacts on Agriculture and Health
Abiela Meek, Dr. Ron Sims and Dr. Brittany Gentry
- Environmental, Social and Economic Ethics of Biofuels: Non-standardized lifecycle assessments can lead to confusion and lack of clarity
Hannah Staker
Track Chairs: Kirsten Sims and Ron Sims
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3:30 PM – 3:45 PM |
Break
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3:45 PM – 5:30 PM |
Poster Competition
Click here for poster titles and presenters
Undergraduate
- Critical Crops: A Meta-Analysis of Grain Environmental Emissions
Andrew Larkin, Abigail Schulte and Kurt Rosentrater
- Development of a Chitosan-gelatin Biopolymer Hydrogel for Bioprinting
Rosalba Mazzotta, Ha Park and Vladimir Reukov
- Improving productivity of algal species P. Renovo using revolving-algal biofilms
Abigail Schulte and Drew Greene
- Increasing Microbial Production of Biotherapeutic Curcumin by Testing Different Feruloyl-CoA Synthases
Kendall Ewert, Kylee Hillman and Jixun Zhan
- Lanthanum-Doped Carbon Dots for Rapid Phosphorus Sensing in Environmental Samples
Samuel Holberg, Jacob Jones, Diana Vanegas and Eric McLamore
- Linking Watershed Characteristics to Multi-Drug Resistant and ESBL Producing Aeromonas spp. and E. coli in Recreational Lakes
Maggie O'Neill, Timothy Neher and Michelle Soupir
- Mechanical Methods for Bioreactor Foam Breaking
Ceaira Howard, Adam Martin, Laurent Saysanavong and Bodee Hancock
- Understanding the Sustainability of High Protein DDGS: Environmental, Social, and Economic Impacts
Hannah Staker and Kurt Rosentrater
Graduate
- A highly versatile fungal glucosyltransferase for specific production of quercetin-7-O-β-D-glucoside and quercetin-3-O-β-D-glucoside in different hosts
Jie Ren, Wenzhu Tang and Jixun Zhan
- Atmospheric Cold Plasma Effects on Properties of Milk Proteins
Shruti Sharma and Rakesh Singh
- Design and screening of multivalent tetrafunctional microparticles for optimal CAR T cell manufacturing
Biaggio Uricoli, A. K. M. Nawshad Hossian, Priscilla Do, Sarwish Rafiq and Erik Dreaden
- Development of a training methodology to use a sensor for glyphosate detection in water
David Bahamon and Diana Vanegas
- Development of an expression plasmid for Pseudomonas putida CBB5
River Copeland, Ryan Summers and Meredith Mock
- Development of Low-Cost Monitoring Systems for Mercury Pollution Near ASGM Sites in Alto Cauca, Colombia
Kelli McCourt, Paulina Rojas-Lamos, Lisseth Casso Hartmann, Irene Velèz-Torres and Diana Vanegas
- The effect of various pre-treatment methods on DDGS to produce total reducing sugars, furfurals and use of pretreated and untreated DDGS for the productions hydrolytic enzyme by fungal strains
Attia Iram, Ali Demirci and Deniz Cekmecelioglu
- Exploration of Impedance-based In Vitro Assays for Breast Cancer Characterization
Kyndra Higgins and Cheryl Gomillion
- Hydroponic Wastewater Reuse for Sustainable Urban Agriculture
Amanda Tan and Diana Vanegas
- Interaction effects of environmental factors on algal biomass productivity and nutrient uptake
Jacob Watkins
- Methods for improving engineered curcumin biosynthesis
Caleb Barton and Jixun Zhan
- Optimizing Algae Biofilm Growth in Wastewater Treatment using Predictive Mathematical Models
Gerald Jones, Dylan Ellis, Zengyan Zhang, Jia Zhao and Ronald Sims
- Quality Control for LIG electrodes: Toward future pandemic prevention
Yifan Tang, Eric McLamore and Diana Vanegas
- Rapid and cost-effective aptasensor to detect Listeria monocytogenes in irrigation water for hydroponic systems
Lisseth Casso-Hartmann, Eric McLamore and Diana Vanegas
- Regulation of Gene Expression by the Twister Sister Ribozyme
Shuyuan Zhang, Ian Brown, Emma Lynch and Ryan Summers
- Rotating Algal Biofilm Reactor (RABR) Biofilm Characterization
Amanda Moravek, Ron Sims and Charles Miller
- Utilization of Greenhouse Gasses for the Production of High-Value Bioproducts
Jaden Storrer, Charles Miller and Jace Parkinson
Postdoc/Miscellaneous
- Bioinspired Superhydrophobic and Liquid-infused Slippery Coatings to Prevent Device-associated Infections and Thrombosis
Ekrem Ozkan, Arnab Mondal, Megan Douglass, Sean Hopkins, Mark Garren, Ryan Devine, Rashmi Pandey, James Manuel, Priyadarshini Singha, James Warnock and Hitesh Handa
- Development of a low-cost enzyme-based biosensor for saliva diagnostics and surveillance of SARS-CoV-2
Geisianny Moreira, Lisseth Casso, Shoumen Datta, Eric McLamore and Diana Vanegas
- miniPCR bio: making science accessible to everyone, everywhere Ally Huang
Track Chairs: Ryan Summers, Sudhagar Mani, Jixun Zhan, Ryan Summers, Ally Huang
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6:30 PM – 8:30 PM |
Awards Banquet and Dinner
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